A judge in the retrial of Amanda Knox and Raffaele Sollecito has ordered a new DNA test on the knife alleged to have been used in the murder of British student Meredith Kercher.
The first day of the hearing took place in Florence, Italy, but neither defendant was in court.
The test on the weapon was requested by prosecutors who won an appeal against the acquittal of Knox and Sollecito, who have already served four years in prison for the crime.
The judge has agreed to test one DNA trace not previously examined because it had been deemed too small.
A court-ordered review in the first appeals trial discredited DNA evidence on the kitchen knife linked to 21-year-old Miss Kercher.
"Before you embark on a Journey of Revenge, Dig Two Graves" Confucius (504 bc)
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