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Measles cases across Europe soared by 400% last year, according to the World Health Organisation.
A total of 21,315 cases were reported on the continent in 2017 and the infection was the cause of 35 deaths.
It came after a record low of 5,273 measles cases the previous year.
WHO said a decline in immunisations, interruptions in vaccine supply, low rates of vaccination among marginalised groups and poor monitoring had contributed to the crisis.
Dr Zsuzsanna Jakab, WHO regional director for Europe, described it as "a tragedy we cannot accept".